Oxygen Starvation Reverses Radiation-Induced Damage To Brain Tissue In Mouse Model
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Likewise Included In: Neurology / Neuroscience ; Radioscopy / Atomic Medicate
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Treating mentality tumors with hale mentality irradiation therapy can scathe hefty head weave, but a new survey in mice reveals that qualifying the o append, or hypoxia, can facilitate roughly of the cognitive constipation caused by the radioactivity. The results are reported in the on-line journal PLoS ONE.
The researchers, led by William Sonntag of University of Oklahoma, uncovered the mice to a clinically relevant regime of radiotherapy, which caused liberal worsening of spacial acquisition start roughly two months post-radiation.
However, when mice were toughened with continuing hypoxia for some iii weeks, rootage one month later actinotherapy pic, they showed important betterment in this domain, which was well-kept for at least two months afterwards reversive to formula o levels.
The irradiation handling besides caused an other declension in contextual erudition and retentiveness, but these deficiencies were transeunt and card-playing inside leash months post-radiation.
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